'Power cycling' is the fancy term for 'have you tried turning it off and back on?' Is Words With Friends 2 not working at all? It may not let you simply close it. That means you probably won't lose any data.
The good news is, if just closing the program works, it's most likely an interface glitch: the whole program didn't fail, just the part you could see. You'll need to either click out to your menu screen and close it independently or select 'close all.' If Words With Friends seems to have crashed, that's where to start. Like many phone apps, Words With Friends doesn't feature a dedicated 'turn this one program off completely' function.
'Have you tried closing the program, then opening it again?' may be IT 101, but it works.
